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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
13.64
Human Site:
T1626
Identified Species:
25
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
T1626
G
G
I
S
A
D
R
T
Q
G
N
I
G
C
G
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1604
Q
L
G
G
Q
Q
T
S
A
L
Q
T
A
G
I
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
T1626
G
G
I
S
T
D
R
T
Q
G
S
I
G
C
G
Dog
Lupus familis
XP_534693
2280
250152
T1696
G
A
S
S
A
D
R
T
Q
G
N
L
G
C
V
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
R1623
A
G
G
S
S
T
D
R
T
P
G
N
V
A
C
Rat
Rattus norvegicus
NP_001101807
1374
149708
Q814
A
Q
P
S
Q
D
G
Q
D
S
V
T
E
R
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
P1586
N
G
Q
L
G
Q
Q
P
P
T
L
Q
T
T
G
Chicken
Gallus gallus
XP_415317
2195
241321
S1612
G
G
N
A
A
D
R
S
Q
G
S
T
G
P
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
G1533
L
Q
S
S
Q
Q
S
G
G
Q
S
A
G
T
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
T2040
P
Q
V
Q
P
M
E
T
N
E
I
K
Q
E
P
Honey Bee
Apis mellifera
XP_393643
1982
216109
P1422
D
E
E
E
V
E
P
P
A
I
V
V
Y
L
V
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
T2219
M
I
L
A
D
P
A
T
V
A
P
I
N
A
Q
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
E567
A
S
S
S
E
N
K
E
N
L
P
K
V
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
0
86.6
73.3
N.A.
13.3
13.3
N.A.
13.3
60
N.A.
13.3
N.A.
6.6
0
13.3
6.6
P-Site Similarity:
100
6.6
93.3
80
N.A.
20
13.3
N.A.
20
80
N.A.
20
N.A.
13.3
13.3
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
8
0
16
24
0
8
0
16
8
0
8
8
16
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
24
8
% C
% Asp:
8
0
0
0
8
39
8
0
8
0
0
0
0
0
0
% D
% Glu:
0
8
8
8
8
8
8
8
0
8
0
0
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
31
39
16
8
8
0
8
8
8
31
8
0
39
8
31
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
16
0
0
0
0
0
0
8
8
24
0
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
16
0
0
0
% K
% Leu:
8
8
8
8
0
0
0
0
0
16
8
8
0
8
8
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
0
0
8
0
0
16
0
16
8
8
0
0
% N
% Pro:
8
0
8
0
8
8
8
16
8
8
16
0
0
8
8
% P
% Gln:
8
24
8
8
24
24
8
8
31
8
8
8
8
0
8
% Q
% Arg:
0
0
0
0
0
0
31
8
0
0
0
0
0
8
0
% R
% Ser:
0
8
24
54
8
0
8
16
0
8
24
0
0
0
0
% S
% Thr:
0
0
0
0
8
8
8
39
8
8
0
24
8
24
0
% T
% Val:
0
0
8
0
8
0
0
0
8
0
16
8
16
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _